|
Symbol Name ID |
Lox
lysyl oxidase MGI:96817 |
| Darker colors indicate more annotations |
| Human Phenotypes | Intracranial hemorrhage |
Subarachnoid hemorrhage |
Bruising susceptibility |
Bicuspid aortic valve |
Cardiomegaly |
Ascending aortic dissection |
Aortic aneurysm |
Abdominal aortic aneurysm |
Thoracic aortic aneurysm |
Aortic root aneurysm |
Ascending tubular aorta aneurysm |
Descending thoracic aorta aneurysm |
Aortic dissection |
Descending aortic dissection |
Aortic rupture |
Mucoid extracellular matrix accumulation |
Patent ductus arteriosus |
Carotid artery dilatation |
Carotid artery stenosis |
Anterior cerebral artery stenosis |
Middle cerebral artery stenosis |
Posterior cerebral artery stenosis |
Dilatation of the cerebral artery |
Moyamoya phenomenon |
Coronary artery aneurysm |
Coronary artery atherosclerosis |
Premature coronary artery atherosclerosis |
Coronary artery dissection |
Peripheral arterial stenosis |
Cystic medial necrosis |
Stroke |
Ischemic stroke |
Transient ischemic attack |
Abnormal left ventricular function |
Aortic regurgitation |
Hypertension |
Hypovolemia |
Cutis marmorata |
Livedo reticularis |
| Disease(s) Associated with LOX | |||||||||||||||||||||||||||||||||||||||
| Menkes disease | |||||||||||||||||||||||||||||||||||||||
| thoracic aortic aneurysm |
| Mouse Phenotypes | abnormal blood vessel morphology |
abnormal pulmonary artery morphology |
pulmonary artery stenosis |
abnormal aorta wall morphology |
abnormal aorta elastic tissue morphology |
decreased aorta elastin content |
abnormal aorta smooth muscle morphology |
decreased aorta wall thickness |
abnormal descending thoracic aorta morphology |
supravalvar aortic stenosis |
aorta stenosis |
aortic aneurysm |
abnormal blood vessel elastic tissue morphology |
heart left ventricle hypertrophy |
heart right ventricle hypertrophy |
abnormal blood flow velocity |
hemothorax |
hemorrhage |
hemoperitoneum |
semilunar valve regurgitation |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Loxb2b370.2Clo/Loxb2b370.2Clo | |||||||||||||||||||||
| Loxtm1Ikh/Loxtm1Ikh | |||||||||||||||||||||
| Loxtm1Soin/Loxtm1Soin | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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